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Keep an eye on Carefully (two)pentobarbital will decrease the extent or effect of suvorexant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. Solid CYP3A4 inducers could lower suvorexant efficacy; if improved suvorexant dose necessary, don't exceed 20 mg/working day
pentobarbital will reduce the level or result of finasteride by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unidentified.
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Keep track of Carefully (one)pentobarbital will minimize the extent or result of osilodrostat by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will decrease the level or impact of carbamazepine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
pentobarbital will decrease the extent or result of buspirone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
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pentobarbital will reduce the level or result of clozapine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will lessen the level or outcome of cannabidiol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Closely. Consider an increase in cannabidiol dosage (dependant on clinical reaction and tolerability) when coadministered with a solid CYP3A4 inducer.
fentanyl transdermal and pentobarbital both maximize sedation. Stay away from or Use Alternate Drug. Restrict use to patients for whom option procedure alternatives are insufficient
pentobarbital will minimize the extent or impact of nelfinavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
pentobarbital will decrease the level or impact of alosetron by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Mysterious.